On April 26, 2012, six people entered an Isolated Confined Environment with the mission to simulate a trip to Mars. Their mission was a catastrophic failure.

影片围绕着心理学家皮特与他被“鬼混”侵扰的病人之间展开，随着病情研究的深入，隐藏在恐惧背后的可怕事件也将渐渐浮出水面。